Orforglipron · Metabolic
Orforglipron dosage by bodyweight
Reference dose ranges scaled across bodyweight bands, anchored to the most-cited research dose (12000 mcg @ 75 kg). Educational only — never a recommendation.
| Bodyweight band | Reference dose range | At U-100 (1 mg/mL) | Vol. on U-100 (5 mg / 2 mL) | 5× t½ elapsed |
|---|---|---|---|---|
| <60 kg / <132 lb | 7480–10120 mcg | 7.48–10.12 mL | 299–405 units2.99–4.05 mL | — |
| 60–75 kg / 132–165 lb | 9180–12420 mcg | 9.18–12.42 mL | 367–497 units3.67–4.97 mL | — |
| 75–90 kg / 165–198 lb | 11220–15180 mcg | 11.22–15.18 mL | 449–607 units4.49–6.07 mL | — |
| 90–105 kg / 198–231 lb | 13260–17940 mcg | 13.26–17.94 mL | 530–718 units5.30–7.18 mL | — |
| >105 kg / >231 lb | 15300–20700 mcg | 15.30–20.70 mL | 612–828 units6.12–8.28 mL | — |
Volume column assumes a standard 5 mg vial reconstituted with 2 mL bacteriostatic water (concentration 2.5 mg/mL); insulin units shown for a U-100 syringe. No published half-life on file for Orforglipron; the elapsed-time column is hidden.
Orforglipron by goal
Read Orforglipron's profile and dosing through a specific research-goal lens.
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Educational use only
This calculator is provided for research and educational purposes. Outputs are derived from the values you enter. Always verify your math and consult a licensed physician before acting on any result.