Tirzepatide · Metabolic
Tirzepatide dosage by bodyweight
Reference dose ranges scaled across bodyweight bands, anchored to the most-cited research dose (5000 mcg @ 75 kg). Educational only — never a recommendation.
| Bodyweight band | Reference dose range | At U-100 (1 mg/mL) | Vol. on U-100 (5 mg / 2 mL) | 5× t½ elapsed |
|---|---|---|---|---|
| <60 kg / <132 lb | 3117–4217 mcg | 3.12–4.22 mL | 125–169 units1.25–1.69 mL | 25 d |
| 60–75 kg / 132–165 lb | 3825–5175 mcg | 3.83–5.17 mL | 153–207 units1.53–2.07 mL | 25 d |
| 75–90 kg / 165–198 lb | 4675–6325 mcg | 4.67–6.33 mL | 187–253 units1.87–2.53 mL | 25 d |
| 90–105 kg / 198–231 lb | 5525–7475 mcg | 5.53–7.47 mL | 221–299 units2.21–2.99 mL | 25 d |
| >105 kg / >231 lb | 6375–8625 mcg | 6.38–8.63 mL | 255–345 units2.55–3.45 mL | 25 d |
Volume column assumes a standard 5 mg vial reconstituted with 2 mL bacteriostatic water (concentration 2.5 mg/mL); insulin units shown for a U-100 syringe. Five half-lives is the conventional washout window where ~3% of peak plasma remains — a useful "next dose due" anchor for Tirzepatide (t½ 5.0 d).
Tirzepatide by goal
Read Tirzepatide's profile and dosing through a specific research-goal lens.
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Educational use only
This calculator is provided for research and educational purposes. Outputs are derived from the values you enter. Always verify your math and consult a licensed physician before acting on any result.