DoseVault
Metabolic Compound

Tesofensine + Metoprolol (Tesomet)

Tesofensine paired with metoprolol (Tesomet) to control HR while preserving weight loss.

Scientific Overview

Tesomet is a fixed-dose combination of tesofensine (a triple monoamine reuptake inhibitor) with metoprolol developed by Saniona. The metoprolol component is intended to blunt cardiovascular activation while maintaining the weight-loss efficacy of tesofensine. Phase 2 trials in hypothalamic obesity and Prader-Willi syndrome reported significant weight loss.

Key Research Benefits

  • ✓Controls tesofensine-induced HR rise
  • ✓Preserves weight loss
  • ✓Studied in Prader-Willi and hypothalamic obesity

Potential Side Effects

⚠Sleep disturbance
⚠Dry mouth
⚠Mood changes

Research Protocols

Common Dosages

Investigational

0.5 mg + 50 mg
Daily, oral

“Phase 2 dosing”

Note: Dosages listed are common research protocols found in peer-reviewed literature and clinical trials. Individual results and requirements may vary significantly in a research context.

Dose Calculator

🧮 Peptide Reconstitution Calculator

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20 Units

or 0.20 mL on a U-100 syringe

Concentration:2.50 mg/mL
Peptide per Unit:25.00 mcg/unit
*Always double-check your calculations. This tool is for educational purposes only.

Explore Tesofensine + Metoprolol (Tesomet)

Where to source

Vendors with public COAs that stock this category. Affiliate links are disclosed.

  • Limitless Life Nootropics
    FL-based research-peptide supplier with Janoshik third-party COAs and a public affiliate program at ~20%.
    COA: JanoshikAffiliate disclosed
    View vendor →
  • SwissChems
    60+ peptide catalog with Janoshik COAs; weekly affiliate payouts.
    COA: JanoshikAffiliate disclosed
    View vendor →
  • Amino Club
    EU/US-facing vendor with a 20% first-order / 10% recurring affiliate model.
    COA: Third-partyAffiliate disclosed
    View vendor →

Tesofensine + Metoprolol (Tesomet) by goal

Read Tesofensine + Metoprolol (Tesomet)'s profile filtered through specific research goals.

Tesofensine + Metoprolol (Tesomet) for Fat Loss

Molecular Profile

small-molecule
C17H24Cl2N + C15H25NO3
1 AA Sequence

Quick Reference

Status
Research Compound
Category
Metabolic
Common Dosage
0.5 mg + 50 mg
Daily, oral

Strictly for research purposes. Not for human consumption.

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Medical Disclaimer

Information provided on DoseVault is for educational and research purposes only. This website does not advocate for the human use of peptides. Peptides are currently sold as research chemicals and are not FDA-approved for human consumption. Always consult a licensed medical professional before considering any protocol.