Semaglutide · Metabolic
Semaglutide dosage by bodyweight
Reference dose ranges scaled across bodyweight bands, anchored to the most-cited research dose (25000 mcg @ 75 kg). Educational only — never a recommendation.
| Bodyweight band | Reference dose range | At U-100 (1 mg/mL) | Vol. on U-100 (5 mg / 2 mL) | 5× t½ elapsed |
|---|---|---|---|---|
| <60 kg / <132 lb | 15583–21083 mcg | 15.58–21.08 mL | 623–843 units6.23–8.43 mL | 35 d |
| 60–75 kg / 132–165 lb | 19125–25875 mcg | 19.13–25.88 mL | 765–1035 units7.65–10.35 mL | 35 d |
| 75–90 kg / 165–198 lb | 23375–31625 mcg | 23.38–31.63 mL | 935–1265 units9.35–12.65 mL | 35 d |
| 90–105 kg / 198–231 lb | 27625–37375 mcg | 27.63–37.38 mL | 1105–1495 units11.05–14.95 mL | 35 d |
| >105 kg / >231 lb | 31875–43125 mcg | 31.88–43.13 mL | 1275–1725 units12.75–17.25 mL | 35 d |
Volume column assumes a standard 5 mg vial reconstituted with 2 mL bacteriostatic water (concentration 2.5 mg/mL); insulin units shown for a U-100 syringe. Five half-lives is the conventional washout window where ~3% of peak plasma remains — a useful "next dose due" anchor for Semaglutide (t½ 7 d).
Semaglutide by goal
Read Semaglutide's profile and dosing through a specific research-goal lens.
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Educational use only
This calculator is provided for research and educational purposes. Outputs are derived from the values you enter. Always verify your math and consult a licensed physician before acting on any result.