Performance Compound

MK-677 (Ibutamoren)

Oral GH secretagogue that cranks appetite, muscle preservation, and bone density.

Scientific Overview

MK-677 signals the pituitary gland to secrete growth hormone. It acts as a potent, orally active growth hormone secretagogue.

Key Research Benefits

  • Increases muscle mass
  • Improves bone density
  • Improves sleep quality
  • Oral administration

Potential Side Effects

Increased appetite
Water retention
Lethargy
Decreased insulin sensitivity

Research Protocols

Common Dosages

Oral Support

10-25 mg
Daily

Orally active; best at night to avoid hunger spikes

Note: Dosages listed are common research protocols found in peer-reviewed literature and clinical trials. Individual results and requirements may vary significantly in a research context.

Dose Calculator

🧮 Peptide Reconstitution Calculator

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mL

Volume of water used to mix.

mcg

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10 Units

or 0.10 mL on a U-100 syringe

Concentration:2.50 mg/mL
Peptide per Unit:25.00 mcg/unit
*Always double-check your calculations. This tool is for educational purposes only.

Explore MK-677 (Ibutamoren)

Where to source

Vendors with public COAs that stock this category. Affiliate links are disclosed.

  • Limitless Life Nootropics
    FL-based research-peptide supplier with Janoshik third-party COAs and a public affiliate program at ~20%.
    COA: JanoshikAffiliate disclosed
  • SwissChems
    60+ peptide catalog with Janoshik COAs; weekly affiliate payouts.
    COA: JanoshikAffiliate disclosed
  • Amino Club
    EU/US-facing vendor with a 20% first-order / 10% recurring affiliate model.
    COA: Third-partyAffiliate disclosed

Quick Explainer

Unlike most peptides, MK-677 is taken orally. It mimics the hunger hormone ghrelin to stimulate growth hormone release, leading to better sleep and muscle preservation.

Stack MK-677 (Ibutamoren) with…

Curated stacking partners researched alongside MK-677 (Ibutamoren). Each link opens a dedicated stack page with combined benefits, side-effect overlap, and half-life considerations.

MK-677 (Ibutamoren) by goal

Read MK-677 (Ibutamoren)'s profile filtered through specific research goals.

Molecular Profile

small-molecule
C27H36N4O5S
1 AA Sequence

Quick Reference

Status
Research Compound
Category
Performance
Common Dosage
10-25 mg
Daily
Plasma decay
100%~3%@ 5× t½

t½ 1.0 d · ~3% remaining at 5.0 d

Strictly for research purposes. Not for human consumption.

Medical Disclaimer

Information provided on DoseVault is for educational and research purposes only. This website does not advocate for the human use of peptides. Peptides are currently sold as research chemicals and are not FDA-approved for human consumption. Always consult a licensed medical professional before considering any protocol.