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Other Compound

Magainin 2

Frog-skin-derived antimicrobial peptide; parent of the pexiganan topical antibiotic.

Scientific Overview

Magainin 2 is a 23-aa cationic alpha-helical peptide isolated from the African clawed frog (Xenopus laevis) by Michael Zasloff in 1987. It forms toroidal pores in microbial membranes. Its analog pexiganan (MSI-78) was studied in two Phase 3 trials for diabetic foot ulcers but failed to meet superiority endpoints, leading to FDA non-approval.

Key Research Benefits

  • ✓Broad-spectrum antibacterial
  • ✓Antifungal activity
  • ✓Membrane-pore mechanism

Potential Side Effects

⚠Local irritation (topical)
⚠Hemolysis at higher concentrations

Research Protocols

Common Dosages

Research

Not established
N/A

“Topical studies only”

Note: Dosages listed are common research protocols found in peer-reviewed literature and clinical trials. Individual results and requirements may vary significantly in a research context.

Dose Calculator

🧮 Peptide Reconstitution Calculator

mg

Total amount of peptide in the vial.

mL

Volume of water used to mix.

mcg

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10 Units

or 0.10 mL on a U-100 syringe

Concentration:2.50 mg/mL
Peptide per Unit:25.00 mcg/unit
*Always double-check your calculations. This tool is for educational purposes only.

Explore Magainin 2

Where to source

Vendors with public COAs that stock this category. Affiliate links are disclosed.

  • Limitless Life Nootropics
    FL-based research-peptide supplier with Janoshik third-party COAs and a public affiliate program at ~20%.
    COA: JanoshikAffiliate disclosed
    View vendor →
  • SwissChems
    60+ peptide catalog with Janoshik COAs; weekly affiliate payouts.
    COA: JanoshikAffiliate disclosed
    View vendor →
  • Amino Club
    EU/US-facing vendor with a 20% first-order / 10% recurring affiliate model.
    COA: Third-partyAffiliate disclosed
    View vendor →

Molecular Profile

linear
C114H180N28O27
23 AA Sequence

Quick Reference

Status
Research Compound
Category
Other
Common Dosage
Not established
N/A

Strictly for research purposes. Not for human consumption.

Related tools

Medical Disclaimer

Information provided on DoseVault is for educational and research purposes only. This website does not advocate for the human use of peptides. Peptides are currently sold as research chemicals and are not FDA-approved for human consumption. Always consult a licensed medical professional before considering any protocol.