DoseVault
Longevity Compound

GDF-11

TGF-beta family ligand controversially linked to age-reversal via parabiosis studies.

Scientific Overview

GDF-11 (Growth Differentiation Factor 11) is a TGF-beta family member famously linked to reversal of cardiac hypertrophy in parabiosis experiments by Amy Wagers' lab (2013). Subsequent work by Novartis/Glass et al. (2015) disputed the original assays and showed GDF-11 can be myo-inhibitory like myostatin. Therapeutic role remains controversial.

Key Research Benefits

  • ✓Possible muscle/cardiac rejuvenation (debated)
  • ✓Neurogenesis (preclinical)

Potential Side Effects

⚠Muscle wasting at high doses
⚠Activin receptor cross-reactivity

Research Protocols

Common Dosages

Research

Not established
N/A

“Animal studies 0.1 mg/kg/day IP”

Note: Dosages listed are common research protocols found in peer-reviewed literature and clinical trials. Individual results and requirements may vary significantly in a research context.

Dose Calculator

🧮 Peptide Reconstitution Calculator

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mcg

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10 Units

or 0.10 mL on a U-100 syringe

Concentration:2.50 mg/mL
Peptide per Unit:25.00 mcg/unit
*Always double-check your calculations. This tool is for educational purposes only.

Explore GDF-11

Where to source

Vendors with public COAs that stock this category. Affiliate links are disclosed.

  • Limitless Life Nootropics
    FL-based research-peptide supplier with Janoshik third-party COAs and a public affiliate program at ~20%.
    COA: JanoshikAffiliate disclosed
    View vendor →
  • SwissChems
    60+ peptide catalog with Janoshik COAs; weekly affiliate payouts.
    COA: JanoshikAffiliate disclosed
    View vendor →
  • Amino Club
    EU/US-facing vendor with a 20% first-order / 10% recurring affiliate model.
    COA: Third-partyAffiliate disclosed
    View vendor →

GDF-11 by goal

Read GDF-11's profile filtered through specific research goals.

GDF-11 for Muscle GainGDF-11 for SleepGDF-11 for Longevity

Molecular Profile

protein
C-terminal active dimer
109 AA Sequence

Quick Reference

Status
Research Compound
Category
Longevity
Common Dosage
Not established
N/A

Strictly for research purposes. Not for human consumption.

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Medical Disclaimer

Information provided on DoseVault is for educational and research purposes only. This website does not advocate for the human use of peptides. Peptides are currently sold as research chemicals and are not FDA-approved for human consumption. Always consult a licensed medical professional before considering any protocol.